Targeted drug delivery, sometimes
called smart drug delivery, is a method of delivering medication to a patient
in a manner that increases the concentration of the medication in some parts of
the body relative to others. This means of delivery is largely founded on
nanomedicine, which plans to employ nanoparticle-mediated drug delivery in
order to combat the downfalls of conventional drug delivery. These
nanoparticles would be loaded with drugs and targeted to specific parts of the
body where there is solely diseased tissue, thereby avoiding interaction with
healthy tissue. The goal of a targeted drug delivery system is to prolong,
localize, target and have a protected drug interaction with the diseased
tissue. The conventional drug delivery system is the absorption of the drug
across a biological membrane, whereas the targeted release system releases the
drug in a dosage form. The advantages to the targeted release system is the
reduction in the frequency of the dosages taken by the patient, having a more
uniform effect of the drug, reduction of drug side-effects, and reduced
fluctuation in circulating drug levels. The disadvantage of the system is high
cost, which makes productivity more difficult and the reduced ability to adjust
the dosages.
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