Nerve agents, sometimes also
called nerve gases, are a class of organic chemicals that disrupt the
mechanisms by which nerves transfer messages to organs. The disruption is
caused by the blocking of acetylcholinesterase, an enzyme that catalyzes the
breakdown of acetylcholine, a neurotransmitter.
Poisoning by a nerve agent leads
to constriction of pupils, profuse salivation, convulsions, and involuntary
urination and defecation, with the first symptoms appearing in seconds after
exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to
the loss of the body's control over respiratory and other muscles. Some nerve
agents are readily vaporized or aerosolized, and the primary portal of entry
into the body is the respiratory system. Nerve agents can also be absorbed
through the skin, requiring that those likely to be subjected to such agents
wear a full body suit in addition to a respirator.
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